Are you ready to optimize your mind, body, and spirit? Join Ben Greenfield, a world-renowned health and fitness expert, as he shares cutting-edge insights on biohacking, fitness, nutrition, and wellness. Whether you're a seasoned athlete, a biohacking enthusiast, or simply looking to improve your overall well-being, this channel is your go-to resource.
What You’ll Find Here:
-Ben Greenfield Life video podcasts with top experts in health and wellness
-In-depth tutorials on biohacking and advanced fitness techniques
-Nutrition advice and recipes to fuel your body and mind
-Personal vlogs and behind-the-scenes content from Ben’s life
-Tips for longevity, anti-aging, and enhancing performance
New Videos Every Week!
Don’t miss out on our weekly uploads that will empower you to live your best life. Hit the subscribe button and ring the bell to stay updated!
Ben Greenfield Life
Do GLP-1 drugs really cause muscle loss? Turns out perhaps less than what we thought…here’s what you need to know, from: www.cell.com/cell-reports-medicine/fulltext/S2666-…
Based on this latest study, GLP-1 drugs seem to induce a loss of liver mass that exceeds a loss in muscle mass. The specific numbers from the mouse data are striking: liver mass decreased by 26% with sedentary “bed-rest” type of simulation alone, 37% with semaglutide, and 55% with survodutide. Compare that to muscle, where the absolute decreases were only modest!
The broader framing of the paper is that the muscle loss panic around GLP-1 agonists is overblown. In many cases, relative muscle mass actually improved, and obese mice on semaglutide ran nearly as well as lean controls on treadmill tests!
The liver finding matters because it reframes what "lean body mass loss" actually means on a DEXA or body comp scan. The study emphasizes that lean body mass includes bone, organs, and other tissues - and that LIVER mass dropping more than muscle mass helps explain why body composition measures can overstate the impression of muscle loss.
BTW, in case you’re wondering why liver mass dropped, it was visceral organ fat and glycogen depletion - again, *not* skeletal muscle wasting!
2 months ago | [YT] | 10
View 0 replies
Ben Greenfield Life
Spermidine for “anti-aging”? Here’s what you need to know: oxfordhealthspan.com/blogs/aging-well/spermidine-a…
2 months ago | [YT] | 9
View 2 replies
Ben Greenfield Life
The effects of wearing a continuous glucose monitor are generally studied in participants with diabetes, but this new study on non-diabetics shows great promise for CGM’s when it comes to successful weight loss: pubmed.ncbi.nlm.nih.gov/41700684
2 months ago | [YT] | 9
View 0 replies
Ben Greenfield Life
CBN (not CBD) strikes again with a study backing up what other research has shown: it’s *fantastic* for sleep quality (but I only use it when traveling, so I maintain sensitivity) - pubmed.ncbi.nlm.nih.gov/41698831
2 months ago | [YT] | 6
View 2 replies
Ben Greenfield Life
Eating more bitter foods (including dark chocolate and broccoli, which I never thought bitter but…whatever…) might be associated with better blood sugar outcomes: pubmed.ncbi.nlm.nih.gov/41512656. Here’s my go-to bitters capsule “pre-carb”: @GetKion www.getkion.com/products/lean
2 months ago | [YT] | 7
View 0 replies
Ben Greenfield Life
Feel “weird” during an NAD IV? Here are the insider tips from a top doctor, Dr. Joseph Purita, to make things smoother:
The first is TMG (trimethylglycine, also called Betaine). TMG acts as a methyl donor. After an IV NAD infusion, the body is flooded with nicotinamide (NAM). Clearing the NAM requires methyl groups, which the TMG supplies. The surge of NAM will increase homocysteine levels and drain methyl group levels. Do the TMG prior to starting the IV.
The second recommendation is to sip on coffee while undergoing IV NAD. The caffeine in coffee upregulates a key NAD+ recycling enzyme (NMNAT2), which converts NMN into NAD+. Caffeine also blocks adenosine receptors, which are also responsible for the uncomfortable symptoms patients develop.
A final trick is to photoactivate the NAD with red light before adding it to the IV bag. NADH produced during photoactivation isn't "lost" - it is immediately re-oxidized to NAD+ by Complex I in the mitochondria.
Leave your questions, comments, and feedback below - and stay tuned for the podcast release soon by subscribing to my newsletter at bengreenfieldlife.com/.
2 months ago | [YT] | 11
View 0 replies
Ben Greenfield Life
One of the top questions I get about young plasma exchange (YPE): “What if the donor was vaccinated? Does that mean I’m getting spike proteins or mRNA injected into me?”
Short answer: No. Here’s the breakdown...
Vaccine mRNA clears from the blood within 1 to 3 weeks post-shot. Spike antigen is gone by day 14 to 28. By the time a donor gives plasma, weeks or months later, there’s nothing measurable left. You’re not getting a “backdoor vaccine”.
A 2025 Kaiser/AABB analysis tracked 7,773 transfusion recipients who got plasma from vaccinated donors. There was no increase in thrombosis, respiratory complications, or mortality.
Reputable young plasma centers already require a 56-day minimum wait after any vaccination before a donor can qualify. That’s 8 weeks, well beyond the clearance window for both mRNA and spike antigen.
The studies fueling this concern are about viral evolution under population-level immune pressure, not what’s inside a plasma bag. Selection pressure happens inside infected people, where the virus is actively replicating, but young, fresh frozen plasma contains no replicating virus.
Plasma is NOT a vaccine vector. FDA, AABB, and large-scale real-world data all agree: blood from vaccinated donors carries no demonstrated transfusion risk.
I’ve gone deep on young plasma exchange with one of the leading physicians in this space, Dr. Khanh Nguyen, on the Boundless Life podcast. The science and the protocols are here:
bengreenfieldlife.com/podcast/khanh-nguyen/
bengreenfieldlife.com/podcast/austinplasma/
bengreenfieldlife.com/austinregen
2 months ago | [YT] | 9
View 2 replies
Ben Greenfield Life
If you are struggling with the symptoms of metabolic issues, such as blood glucose fluctuations, high body fat percentage/inability to lose weight, low heart rate variability, high heart rate, etc., then it’s pretty likely you would benefit from not eating for ~3 hours prior to bedtime and/or not eating for like it~3 hours after you wake: pubmed.ncbi.nlm.nih.gov/41674465/
2 months ago | [YT] | 23
View 1 reply
Ben Greenfield Life
You need to turn *this many* carbs to maximize muscle growth…the answer is a little nuanced (e.g., Do you train fasted? Do you train high volume? Do you train multiple times in a day?)… But still less carbs than you might think: mennohenselmans.com/you-need-this-many-carbs-to-ma…
2 months ago | [YT] | 9
View 0 replies
Ben Greenfield Life
Born to run? Competitive runners have better genes for resistance to injury: "Collagen Gene Polymorphisms Previously Associated with Resistance to Soft-Tissue Injury Are More Common in Competitive Runners Than Nonathletes."
journals.lww.com/nsca-jscr/fulltext/2023/04000/col…
2 months ago | [YT] | 21
View 0 replies
Load more